[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$frva_nlWEzWuXLMpvAKwNdN5OqEOUWOv5dZ6o3VF2B4U":3},{"code":4,"msg":5,"data":6},200,"操作成功",{"id":7,"title":8,"content":9,"digest":10,"source":10,"coverPath":11,"thumbsCoverPath":12,"isTop":13,"isShow":14,"baseClick":13,"clickCount":15,"createTime":16,"typeId":17,"isNewest":18,"newsInfoTypeRespVo":19,"voiceUrl":22,"voiceSize":23,"taskId":24,"releaseTime":25,"titleEn":26,"contentEn":27,"voiceUrlEn":28,"taskIdEn":29,"voiceSizeEn":30},1382,"科研新突破！我国科学家破解植物细胞全能性世纪难题","\u003Cp>\u003Cstrong class=\"ql-lineHeight-1-75\" style=\"font-size: 18px; color: rgb(255, 153, 0);\">单个植物体细胞如何发育为完整植株？9月16日，著名学术期刊《细胞》在线发表中国科学家的科研成果，首次完整揭示了这一全过程。该成果不仅破解了困扰科学界百余年的“植物细胞全能性”机制之谜，也为作物遗传改良与高效再生提供了全新理论支撑。\u003C\u002Fstrong>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cimg alt=\"undefined\" src=\"https:\u002F\u002Fimage.51xinwei.com\u002F2025\u002F09\u002F23016a8663ae4dff894e4b05c738eb5c\u002Fa60f6dc97bcb43d3b8737195fd50920c.webp\" width=\"undefined\" height=\"undefined\" style=\"display: block; margin: auto;\">\u003Cp class=\"ql-align-center\">\u003Cspan class=\"ql-lineHeight-1-75\" style=\"color: rgb(187, 187, 187);\">气孔前体细胞的两条发育路径的模式图。受访者提供\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">1902年“植物细胞全能性”概念被提出，即植物细胞可脱分化形成类似受精卵的全能干细胞，进而发育为完整植株，但其背后的分子机制始终未解。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">为揭开谜团，2005年起，论文通讯作者、山东农业大学张宪省教授率领的科研团队以拟南芥为研究对象开启探索。20年来，团队先后构建了单个体细胞直接发育成胚胎的实验技术体系，以及诱导单细胞起源的体细胞胚胎发生的稳定体系，并首次发现细胞全能性激活的“开关”是大量生长素的积累。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cimg alt=\"undefined\" src=\"https:\u002F\u002Fimage.51xinwei.com\u002F2025\u002F09\u002F5fb69dd1297c4e3db927f4c0a4de4a74\u002Fa16bb9def050434399e231652b9b0833.webp\" width=\"undefined\" height=\"undefined\" style=\"display: block; margin: auto;\" class=\"ql-align-center\">\u003Cp class=\"ql-align-center\">\u003Cspan style=\"color: rgb(187, 187, 187);\" class=\"ql-lineHeight-1-75\">植物体细胞重编程形成全能干细胞的分子调控网络。受访者提供\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">利用应用扫描电镜、先进的单细胞测序、显微切割转录组测序与活体成像等前沿技术，科研人员首次捕捉到单个植物细胞的分裂全过程，直观证实了植物细胞全能性的“单细胞起源”，回答了学术界长期存在的疑惑。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">团队通过深入研究，找到了触发细胞全能性的“关键钥匙”：叶片气孔前体细胞特有的基因SPCH，与人工诱导高表达的基因LEC2，二者协同作用形成“分子开关”。“就像转动一把锁需要两把钥匙，缺一不可。”张宪省说。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp class=\"ql-align-center\">\u003Cbr>\u003C\u002Fp>\u003Cimg alt=\"undefined\" src=\"https:\u002F\u002Fimage.51xinwei.com\u002F2025\u002F09\u002F51e53fee57b244b697d14cc03c881b9c\u002F46dd5f5f23434a65adc6143c046f775a.webp\" width=\"undefined\" height=\"undefined\" style=\"display: block; margin: auto;\" class=\"ql-align-center\">\u003Cp class=\"ql-align-center\">\u003Cspan class=\"ql-lineHeight-1-75\" style=\"color: rgb(187, 187, 187);\">张宪省教授（右）和苏英华教授在讨论。受访者提供\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">论文通讯作者之一、山东农业大学教授苏英华介绍，团队完整记录了细胞命运重塑的完整路径，揭示了关键的命运分岔点。在从“普通细胞”转变为“全能干细胞”的关键过渡状态下，细胞发生了深度的染色质重塑，大量沉默的基因被逐步激活，细胞命运轨迹由此产生分岔，为全能性的建立打开了大门。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">该研究在国际上首次全面解析了单个植物体细胞重编程形成全能干细胞并再生完整植株的分子机理。中国科学院院士种康认为，该研究不仅深化了对植物细胞全能性机理的理解，也为破解农业生物技术长期存在的“再生瓶颈”开辟了新路径。据介绍，目前，该体系在小麦、玉米和大豆等作物的实验正同步推进。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp class=\"ql-align-justify\">\u003Cspan style=\"color: rgb(187, 187, 187);\">【新闻来源】河南日报 （喻思 南王静） \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.sohu.com\u002Fa\u002F935977138_121375869?scm=10001.1104_13-100000-0_922.0-0.0.a2_5X162X1653&spm=smpc.channel_159.block3_218_AB1PKt_1_fd.8.17585340789611UGsQYi_1104\" rel=\"noopener noreferrer\" target=\"_blank\" style=\"color: rgb(187, 187, 187);\">http:\u002F\u002Fi9n.cn\u002FTMBT6\u003C\u002Fa>\u003C\u002Fp>\u003Cp class=\"ql-align-justify\">\u003Cspan style=\"color: rgb(187, 187, 187);\">（本网转发此文章，旨在为读者提供更多的信息资讯，所涉内容不构成投资、消费建议。文章事实如有疑问，请与有关方核实，文章观点非本网观点，仅供读者参考。）\u003C\u002Fspan>\u003C\u002Fp>","","https:\u002F\u002Fimage.51xinwei.com\u002F2025\u002F09\u002Fa6a0cc19d6374ee4abb7717c2a4e8eb7\u002F超限探索.jpg","https:\u002F\u002Fimage.51xinwei.com\u002F2025\u002F09\u002Fthumbs\u002Fa6a0cc19d6374ee4abb7717c2a4e8eb7\u002F超限探索.jpg",0,1,315,"2025-09-22 17:49",2,false,{"id":17,"name":20,"enName":21},"芯位视野","Xinwei Vision","https:\u002F\u002Fxinwei-dev-test.oss-cn-shenzhen.aliyuncs.com\u002Fintelligent\u002Faudio%3A74538d15-1014-463f-81b9-e31c43becca7%3A0.wav?Expires=1758544069&OSSAccessKeyId=LTAI5tNvY2RkKjZw4LLWsrPK&Signature=iUbhyfqKAPGr0P4aSvIZEOzAu9o%3D",4909418,"74538d15-1014-463f-81b9-e31c43becca7","2025-09-22 17:43","Scientific Breakthrough! Chinese Scientists Crack the Century-Old Mystery of Plant Cell Totipotency","\u003Cp>\u003Cstrong class=\"ql-lineHeight-1-75\" style=\"font-size: 18px; color: rgb(255, 153, 0);\">How can a single plant somatic cell develop into a complete plant? On September 16th, a renowned academic journal \"Cell\" published the research results of Chinese scientists online, for the first time revealing the entire process. This achievement not only solves the century-old mystery of the \"plant cell totipotency\" mechanism, but also provides new theoretical support for crop genetic improvement and efficient regeneration.\u003C\u002Fstrong>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cimg alt=\"undefined\" src=\"https:\u002F\u002Fimage.51xinwei.com\u002F2025\u002F09\u002F23016a8663ae4dff894e4b05c738eb5c\u002Fa60f6dc97bcb43d3b8737195fd50920c.webp\" width=\"undefined\" height=\"undefined\" style=\"display: block; margin: auto;\">\u003Cp class=\"ql-align-center\">\u003Cspan class=\"ql-lineHeight-1-75\" style=\"color: rgb(187, 187, 187);\">Model diagram of two developmental pathways of stomatal precursor cells. Provided by the respondent.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">The concept of \"plant cell totipotency\" was proposed in 1902, meaning that plant cells can dedifferentiate to form totipotent stem cells similar to zygotes, which then develop into complete plants, but the underlying molecular mechanisms remained unsolved.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">To uncover this mystery, since 2005, the research team led by Professor Zhang Xiansheng, the corresponding author of the paper, has started exploring using Arabidopsis as the research object. Over 20 years, the team has successively established an experimental system for single somatic cells directly developing into embryos, as well as a stable system for inducing somatic embryogenesis from single cells, and for the first time discovered that the \"switch\" for activating cell totipotency is the accumulation of large amounts of auxin.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cimg alt=\"undefined\" src=\"https:\u002F\u002Fimage.51xinwei.com\u002F2025\u002F09\u002F5fb69dd1297c4e3db927f4c0a4de4a74\u002Fa16bb9def050434399e231652b9b0833.webp\" width=\"undefined\" height=\"undefined\" style=\"display: block; margin: auto;\" class=\"ql-align-center\">\u003Cp class=\"ql-align-center\">\u003Cspan style=\"color: rgb(187, 187, 187);\" class=\"ql-lineHeight-1-75\">Molecular regulatory network for reprogramming of plant somatic cells into totipotent stem cells. Provided by the respondent.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">Using advanced technologies such as scanning electron microscopy, single-cell sequencing, microdissection transcriptome sequencing, and live imaging, researchers have captured the entire division process of a single plant cell, intuitively confirming the \"single-cell origin\" of plant cell totipotency, answering long-standing doubts in the academic community.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">Through in-depth research, the team found the \"key\" to triggering cell totipotency: the gene SPCH specific to leaf stomatal precursor cells, and the gene LEC2 artificially induced to be highly expressed, both work together to form a \"molecular switch.\" \"It's like turning a lock requires two keys, and neither is missing,\" said Zhang Xiansheng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp class=\"ql-align-center\">\u003Cbr>\u003C\u002Fp>\u003Cimg alt=\"undefined\" src=\"https:\u002F\u002Fimage.51xinwei.com\u002F2025\u002F09\u002F51e53fee57b244b697d14cc03c881b9c\u002F46dd5f5f23434a65adc6143c046f775a.webp\" width=\"undefined\" height=\"undefined\" style=\"display: block; margin: auto;\" class=\"ql-align-center\">\u003Cp class=\"ql-align-center\">\u003Cspan class=\"ql-lineHeight-1-75\" style=\"color: rgb(187, 187, 187);\">Professor Zhang Xiansheng (right) and Professor Su Yinghua discussing. Provided by the respondent.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">One of the corresponding authors of the paper, Professor Su Yinghua from Shandong Agricultural University, introduced that the team has completely recorded the entire path of cell fate reshaping and revealed the key points of fate bifurcation. In the critical transitional state from \"ordinary cells\" to \"totipotent stem cells\", the cells underwent deep chromatin remodeling, with many silenced genes being gradually activated, leading to the divergence of cell fate trajectories and opening the door to totipotency.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\" class=\"ql-lineHeight-1-75\">This study comprehensively elucidated for the first time the molecular mechanism of a single plant somatic cell reprogramming into totipotent stem cells and regenerating a complete plant. Academician Zhong Kang of the Chinese Academy of Sciences believes that this study not only deepens the understanding of the mechanism of plant cell totipotency, but also opens up a new path to solve the long-standing \"regeneration bottleneck\" in agricultural biotechnology. According to the introduction, the system is currently being advanced in experiments on crops such as wheat, corn, and soybeans.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp class=\"ql-align-justify\">\u003Cspan style=\"color: rgb(187, 187, 187);\">[News Source] Henan Daily (Yu Si, Nan Wangjing) \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.sohu.com\u002Fa\u002F935977138_121375869?scm=10001.1104_13-100000-0_922.0-0.0.a2_5X162X1653&spm=smpc.channel_159.block3_218_AB1PKt_1_fd.8.17585340789611UGsQYi_1104\" rel=\"noopener noreferrer\" target=\"_blank\" style=\"color: rgb(187, 187, 187);\">http:\u002F\u002Fi9n.cn\u002FTMBT6\u003C\u002Fa>\u003C\u002Fp>\u003Cp class=\"ql-align-justify\">\u003Cspan style=\"color: rgb(187, 187, 187);\">（This article is forwarded by this website to provide readers with more information and news. The content does not constitute investment or consumption advice. If there are any questions about the facts of the article, please verify with the relevant parties. The views of the article are not the views of this website and are for reference only.）\u003C\u002Fspan>\u003C\u002Fp>","https:\u002F\u002Fxinwei-dev-test.oss-cn-shenzhen.aliyuncs.com\u002Fintelligent\u002Faudio%3Ad70b0ceb-9868-44c1-82fd-4d2ac39db7d4%3A0.wav?Expires=1774838467&OSSAccessKeyId=LTAI5tNvY2RkKjZw4LLWsrPK&Signature=%2BuBpwQLHJhdu8uvPxeE%2BnulwEtw%3D","d70b0ceb-9868-44c1-82fd-4d2ac39db7d4",6695086]